Colin Russell

Professor of Applied Evolutionary Biology

I study the evolution of pathogens and the host responses that control them. Most of my research focuses on influenza viruses but I am interested in pathogens of all kinds.

I received my BSc from Emory University in 2001 and my PhD from the University of Cambridge in 2006. Following my PhD, I remained at the University of Cambridge, first as a Junior Research Fellow of Clare College and then as a Royal Society University Research Fellow. In 2017, I moved to AMC to head the Laboratory of Applied Evolutionary Biology.

I am a current ERC Consolidator Awardee (2019-2024) and ZonMw/NWO VICI Laureate (2021-2026).

A complete list of publications can be found here - Google Scholar 

Key publications:

Morris DH, VN Petrova, FW Rossine, E Parker, BT Grenfell, R Neher, SA Levin, CA Russell. Asynchrony between virus diversity and antibody selection limits influenza virus evolution.

eLife. 9:e62105. (2020)

Petrova VN, B Sawatsky, AX Han, BM Laksono, L Walz, E Parker, K Pieper, CA Anderson, RD de Vries, A Lanzavecchia, P Kellam, V von Messling, RL de Swart, CA Russell. Incomplete genetic reconstitution of B cell pools contributes to prolonged immunosuppression after measles.

Science Immunology. 4:eaay6125. (2019)

Han A, S Maurer-Stroh, CA Russell. Individual immune selection pressure has limited impact on seasonal influenza virus evolution.

Nature Ecology and Evolution. 10.1038/s41559-018-0741-x. (2018)

Petrova VN, CA Russell. The evolution of seasonal influenza viruses.

Nature Reviews Microbiology. 16:47-60. (2018)

Russell CA, MD de Jong. Infectious disease management must be evolutionary.

Nature Ecology and Evolution. 1:1053-1055. (2017)

Lipsitch M, WS Barclay, R Raman, CJ Russell, J Belser, S Cobey, P Kasson, JO Lloyd-Smith, S Maurer-Stroh, S Riley, C Beauchemin, T Bedford, T Friedrich, A Handel, S Herfst, P Murcia, B Roche, C Wilke, CA Russell. Viral factors in influenza pandemic risk assessment.

eLife. 5:e18491. (2016)

Bedford T, S Riley, IG Barr, S Broor, M Chadha, NJ Cox, RS Daniels, CP Gunasekaran, AC Hurt, A Kelso, A Klimov, NS Lewis, X Li, JW McCauley, T Odagiri, V Potdar, A Rambaut, Y Shu, E Skepner, DJ Smith, MA Suchard, M Tashiro, D Wang, X Xu, P Lemey, CA RussellGlobal circulation patterns of seasonal influenza viruses vary with antigenic drift.

Nature. 523:217-220. (2015)

Katzelnick LC, JM Fonville, GD Gromowski, SL James, TC Pierson, P Buchy, E Harris, JG Aaskov, JL Muñoz-Jordán, N Vasilakis, RV Gibbons, RB Tesh, LA Van Blargan, CA Russell, ADME Osterhaus, RAM Fouchier, CP Simmons, EC Holmes, E Harris, SS Whitehead, DJ Smith. Dengue viruses cluster antigenically but not as discrete serotypes

Science. 349:1338-1343. (2015)

Russell CA, P Kasson, RO Donis, J Dunbar, J Asher, S Burke, CT Davis, R Garten, S Gnanakaran, S Hay, S Herfst, N Lewis, J Lloyd-Smith, C Macken, S Maurer-Stroh, E Neuhaus, C Parrish, K Pepin, A Rambaut, S Riley, S Shepard, DL Smith, D Suarez, S Trock, M-A Widdowson, D George, M Lipsitch, JD Bloom. Improving pandemic influenza risk assessment

eLife. 3:e03883. (2014)

Neher R, CA Russell, BI Shraiman. Predicting evolution from the shape of genealogical trees

eLife. 3:e03568. (2014)

Fonville JM, SH Wilks, SL James, M Aban, L Xue, TC Jones, M Ventresca, A Fox, LNMH Pham Q, Tran ND, Y Wong, A Mosterin, LC Katzelnick, G van der Net, E Skepner, CA Russell, TD Kaplan, GF Rimmelzwaan, N Masurel, JC de Jong, A Palache, WEP Beyer, LQM Nguyen, H Wertheim, A Hurt, ADME Osterhaus, IG Barr, RAM Fouchier, P Horby, DJ Smith. Antibody landscapes after influenza virus infection or vaccination

Science. 346:996-1000. (2014)

Koel BF,  DF Burke, TM Bestebroer, S van der Vliet, GCM Zondag, G Vervaet, E Skepner, NS Lewis, MIJ Spronken, CA Russell, MY Eropkin, AC Hurt, IG Barr, JC de Jong, GF Rimmelzwaan, ADME Osterhaus, RAM Fouchier, DJ Smith. Substitutions near the receptor binding site determine major antigenic change during influenza virus evolution

Science. 342:976-979. (2013)

Russell CA, J Fonville, AEX Brown, DF Burke, DL Smith, S James, S Herfst, S van Boheeman, M Linster, EJ Schwauren, L Katzelnick, A Mosterin, T Kuiken, E Maher, G Neumann,  ADME Osterhaus, Y Kawaoka, RAM Fouchier, DJ Smith. The potential for airborne transmissible avian A/H5N1 influenza viruses to evolve in nature

Science. 336:1541-1547. (2012)

Russell CA, TC Jones, IG Barr, NJ Cox, R Garten, V Gregory, I Gust, AW Hampson, AJ Hay, AC Hurt, JC de Jong, AI Klimov, T Kageyama, N Komadina, AS Lapedes, YP Lin, A Mosterin, M Obuchi, T Odagiri, ADME Osterhaus, GF Rimmelzwaan, MW Shaw, E Skepner, K Stohr, M Tashiro, RAM Fouchier, DJ Smith. The global circulation of seasonal influenza A(H3N2) viruses

Science. 320:340-346. (2008)